The rule that matters most
Do not stop steroids abruptly after more than about three weeks of treatment. Your adrenal glands stop producing cortisol during treatment and take time to restart. Stopping suddenly can cause an adrenal crisis — collapse, low blood pressure, and it can be fatal.
Reduction is gradual and supervised, slower the longer you have been on treatment and the lower the dose gets.
Withdrawal symptoms
Fatigue, aching, low mood, nausea and dizziness during reduction are common and usually mean the taper is too fast rather than that the underlying condition has returned.
Steroid-sparing alternatives
For conditions needing long-term control, the aim is always to find something that reduces or replaces the steroid — methotrexate, azathioprine, biologics and others, all under specialist supervision.
Where inflammation is localised, injected, inhaled or topical steroids achieve local effect with far less systemic exposure.