My antihistamines have stopped working. What now?
Usually they have not stopped working — they were never enough on their own.
A nasal corticosteroid spray is the most effective single hay fever treatment, and combining it with an antihistamine works considerably better than either alone. Most people missing control are missing that second half.
Am I using the spray correctly?
Probably not — almost nobody is, and it is the commonest reason sprays "do not work".
- Aim outward, toward the ear on the same side, never up the middle
- Use the opposite hand — right hand, left nostril — which produces the correct angle naturally
- Breathe in gently. Do not sniff hard, which sends it down your throat
Aiming at the septum causes the nosebleeds people blame the spray for.
When should I start treatment?
Before the season, because nasal steroids take one to two weeks to work fully.
Tree pollen: late February. Grass pollen: late April. Weed pollen: June. Starting in the first bad week means a fortnight of unnecessary misery.
Can I use it only on bad days?
No — that is why it seems ineffective. Nasal steroids suppress inflammation continuously and need daily use through the season.
Antihistamines can be taken as needed. The spray cannot.
Which antihistamine is best?
Fexofenadine, cetirizine and loratadine are all non-sedating and all effective, and people respond differently — if one does little, try another.
Avoid the older sedating ones (chlorphenamine, promethazine) if you are driving, working or sitting exams. Buy own-brand: it is the identical drug at a fraction of the price.
Could it be something other than hay fever?
Worth asking, particularly if:
- Symptoms are year-round — suggesting dust mite, pets or mould, which are managed differently
- Only one side is affected, or there is bleeding, facial pain or loss of smell — not typical, and needing assessment
- There is wheeze, chest tightness or a night-time cough — which raises asthma
Why does hay fever matter for asthma?
Because they frequently coexist, and treating only the nose leaves the more serious half untreated. Uncontrolled hay fever makes asthma harder to control.
Any wheeze or breathlessness needs assessing properly rather than being treated as hay fever alone.
Can you give me a steroid injection for my wedding?
No. Depot steroid injections such as Kenalog are no longer recommended for hay fever in the UK — the dose cannot be withdrawn once given, and it suppresses the adrenal system for months.
Some private clinics still offer them. For a specific occasion, a short course of oral steroid alongside optimised treatment is the safer approach.
Do I need allergy testing?
Only where the result would change something. Symptoms every May and June do not need a test to identify grass pollen.
Testing is worth it for year-round symptoms, where identifying dust mite or a pet changes the plan considerably.
Is there anything that cures it?
Immunotherapy comes closest — desensitisation with tablets or injections over about three years, which modifies the allergy rather than suppressing symptoms.
Available on the NHS through allergy clinics for severe hay fever not controlled by anything else, and worth asking about if every summer is a write-off.
What can I take in pregnancy?
Several options are considered safe — certain antihistamines and nasal steroids among them — and saline rinses are entirely safe and genuinely useful.
Do not simply endure it. Tell the GP you are pregnant and the plan will be built around it.