Home

/

Medicines A-Z

/

Terbinafine

Terbinafine

The standard antifungal for nails and skin — effective, slow for nails, and the tablets need bloods first.

Infection

Lamisil, terbinafine hydrochloride

Explained by a GMC-registered GP, not a leaflet

Honest about what we can and cannot prescribe remotely

Side effects given the same weight as benefits

Your NHS records in the room, with your consent

Clinically reviewed by Dr Mohammad Khan · Last reviewed

September 5, 2026

Book a consultation

A 20-minute appointment with a GMC-registered GP for £40. Same-day appointments are usually available, 6am to 10pm, seven days a week.

Private GP care led personally by Dr Mohammad Zubair Khan, GMC 7563469.

Why patients choose Cheshire Clinics

GMC registered doctors badge - every Cheshire Clinics consultation is with a General Medical Council registered GP

GMC-registered

Care led personally by Dr Khan

Royal College of General Practitioners badge - RCGP trained private GP consultations at Cheshire Clinics

RCGP-trained

Attentive, unhurried care that listens properly

Google five star reviews badge - Cheshire Clinics private GP online

Highly rated by patients

Five-star Google reviews from the people we have looked after

Care Quality Commission registered badge - Cheshire Clinics online GP service is registered with the CQC, England's independent regulator of health and social care

CQC-registered

Registered with the Care Quality Commission

Same-Day Appointments
Sick Notes
Private Prescriptions
Blood Tests
Menopause & HRT
Weight Management
Mental Health
Specialist Referrals
Same-Day Appointments
Sick Notes
Private Prescriptions
Blood Tests
Menopause & HRT
Weight Management
Mental Health
Specialist Referrals

What it is

Terbinafine is an antifungal that kills dermatophytes — the fungi responsible for athlete's foot, ringworm, jock itch and fungal nail infection. It works by blocking an enzyme the fungus needs to build its cell membrane.

It comes as a cream, available over the counter, and as tablets, which are prescription-only.

The distinction matters enormously. Cream works well on skin and does essentially nothing for an infected nail — it cannot penetrate the nail plate. Nail infection needs oral treatment for months, and that is a genuinely different decision with genuinely different risks.

What it is used for

Cream

  • Athlete's foot
  • Ringworm of the body
  • Jock itch — fungal infection of the groin
  • Some cases of pityriasis versicolor

Tablets

  • Fungal nail infection, particularly toenails — the main use
  • Extensive or resistant skin infection
  • Scalp ringworm

It does not treat Candida — thrush needs a different antifungal entirely.

How to take it

Cream

  • Once or twice daily, to the affected area and a margin of normal skin around it
  • Athlete's foot: one to two weeks — and keep going for a few days after it looks clear
  • Body ringworm: one to two weeks
  • Dry the area thoroughly first, particularly between the toes

Tablets

  • 250mg once daily
  • Fingernails: six weeks. Toenails: three to six months
  • With or without food

Why nails take so long

The tablet does not clear the existing damaged nail — it stops the fungus so a healthy nail can grow out. Toenails grow roughly 1mm a month, so a full toenail takes twelve to eighteen months to replace.

That means the nail will still look abnormal when you finish the course, and it will keep improving for a year afterwards. Knowing this in advance prevents a great deal of unnecessary disappointment.

Need this reviewed or prescribed?

Book a consultation

Side effects

Cream

Local irritation, redness, itching or stinging. Generally well tolerated.

Tablets — common

  • Nausea, abdominal discomfort, diarrhoea
  • Headache
  • Loss or alteration of taste — recognised, sometimes persisting for weeks after stopping, and occasionally longer. Uncommon but genuinely troublesome when it happens
  • Rash

Tablets — serious

  • Liver injury — uncommon but the reason blood tests are done. Nausea with jaundice, dark urine, pale stools, itching or right-sided abdominal pain means stopping and seeking advice
  • Severe skin reactions — a spreading rash with blistering or mouth ulcers needs urgent assessment
  • Blood disorders, rarely
  • Worsening or triggering of lupus

Not suitable if

Tablets

  • You have significant liver disease, or previous liver injury from terbinafine
  • You have severe kidney impairment
  • You have lupus
  • You are pregnant or breastfeeding — generally avoided

Cream

Only if you are allergic to it. It is otherwise very safe, and is available over the counter for good reason.

The question worth asking first

Is the nail actually fungal? Roughly half of abnormal-looking nails are not. Psoriasis, trauma, and lichen planus all mimic it, and treating those with six months of terbinafine achieves nothing while exposing someone to the risks.

That is why nail clippings for laboratory confirmation are recommended before starting oral treatment — not as a formality, but because the answer changes the plan half the time.

Interactions and monitoring

  • Terbinafine inhibits a liver enzyme (CYP2D6), raising levels of several drugs — notably some antidepressants including fluoxetine and paroxetine, tricyclics, some beta blockers, and tamoxifen
  • Rifampicin reduces terbinafine levels; cimetidine raises them
  • Caffeine is cleared more slowly

Monitoring for tablets

Liver function tests before starting, and again at four to six weeks for longer courses. This is standard practice and is not optional.

A full blood count is checked in longer courses or where there is any concern.

Nail clippings for mycology before starting — the most useful test of all, because it establishes whether the diagnosis is right.

Can we prescribe this?

Yes for both, and the useful part of the consultation differs completely between them.

For skin infection

Terbinafine cream is available over the counter and is cheap. For straightforward athlete's foot or ringworm, a pharmacy is faster and we would say so rather than charge a fee.

For nail infection

This is where a consultation genuinely earns its place, because the decision is more involved than it looks:

  • Confirming it is fungal, ideally with nail clippings — about half are not
  • Arranging baseline liver function tests before starting
  • Reviewing your other medicines, since terbinafine raises the levels of several
  • An honest conversation about whether to treat at all. A symptomless discoloured toenail in a healthy person is a cosmetic problem, and three to six months of tablets with blood monitoring is a real intervention. Doing nothing is a legitimate choice

Where treatment matters more: diabetes, poor circulation, immunosuppression, or nails causing pain or recurrent skin infection.

This page is information, not an offer to supply.

Cost and supply

Terbinafine cream is over the counter and inexpensive — own-brand versions cost a few pounds and are identical to Lamisil.

Tablets are prescription-only and cheap as a generic, though a three to six month course accumulates, and the blood tests are a separate cost on the private route. That total is worth knowing at the outset.

Where not to spend

  • Medicated nail lacquers — amorolfine and similar. Widely sold, expensive over a year, and cure rates for established toenail infection are poor. Reasonable only for very early, superficial involvement
  • Tea tree oil, vinegar soaks and Vicks — popular, and the evidence does not support them for established nail infection
  • Laser nail treatment — costly, and the evidence for durable cure is weak

What costs nothing and prevents recurrence

Drying between the toes, rotating footwear, treating the athlete's foot that reinfects the nail, and not sharing nail clippers. Recurrence rates are high, and this is what changes them.

Stopping or switching

Complete the course. Stopping early is the commonest reason nail treatment fails, and it usually happens because the nail still looks abnormal — which it will.

Stop and seek advice for

  • Jaundice, dark urine, pale stools, persistent nausea or right-sided abdominal pain — possible liver injury
  • A spreading rash, blistering, or mouth ulcers — possible severe skin reaction
  • Loss of taste — not dangerous, but worth discussing, since it occasionally persists

If it has not worked

  • It was never fungal — nail psoriasis or old trauma. The commonest explanation
  • Reinfection from untreated athlete's foot — treat the skin as well as the nail, or it recurs
  • A non-dermatophyte organism, which terbinafine does not cover

Alternatives

  • Itraconazole — oral, covers a broader range including Candida, with different interactions
  • Amorolfine nail lacquer — for very early superficial infection only
  • Clotrimazole or miconazole cream — for skin infection
  • Doing nothing — entirely reasonable for an asymptomatic nail in a healthy person

Common questions

How long until my nail looks normal?

Twelve to eighteen months for a toenail, and the tablets finish long before that.

The medicine stops the fungus; the nail has to grow out. Your nail will still look abnormal on the last day of the course, and that is expected rather than failure.

Will the cream fix my nail?

No. Cream cannot penetrate the nail plate. Nail infection needs oral treatment, or accepting it.

Do I really need a blood test first?

Yes, for the tablets. Terbinafine can affect the liver, and baseline liver function — with a repeat at four to six weeks for longer courses — is standard practice rather than caution for its own sake.

Do I have to treat it at all?

Not necessarily, and this is worth saying plainly. A discoloured toenail causing no symptoms in a healthy person is a cosmetic issue, and three to six months of tablets with monitoring is a genuine intervention.

Treatment matters more if you have diabetes, poor circulation, a suppressed immune system, or the nail is painful or causing repeated skin infections.

Can I drink alcohol?

Moderate drinking is generally acceptable, but heavy drinking is not advisable during a course, since both the drug and alcohol are handled by the liver.

Why has my taste gone strange?

A recognised side effect. It usually returns within weeks of stopping, though occasionally it takes longer. Worth reporting.

Why does it keep coming back?

Usually reinfection from athlete's foot, shoes, or communal floors. Treat the skin alongside the nail, rotate footwear, dry between the toes, and do not share clippers.

Dr Mohammad Zubair Khan, GMC-registered private GP and founder of Cheshire Clinics

Clinically reviewed by Dr Mohammad Zubair Khan, GMC 7563469

Last reviewed

September 5, 2026

How it works

What happens when you book

£40 for a 20-minute appointment with a GMC-registered GP, 6am to 10pm, seven days a week. Membership is optional and never required.
Cheshire Clinics online GP appointment booking confirmation on mobile
01

Book your appointment

Pick a time that suits you — 6am to 10pm, seven days a week, including weekends and bank holidays. £40 for 20 minutes, self-pay, with no insurance to arrange.
5–10 minutes
Online video consultation with a GMC-registered private GP
02

Meet your GP

A 20-minute video or phone consultation with a GMC-registered GP — long enough for a proper conversation about your symptoms, your history and what matters to you.
20 minutes
Diagnostic testing plan including blood test panel, ECG and urine screening
03

Tests and referrals, if you need them

Where testing will actually answer the question, we arrange it — blood tests and health screening through our laboratory partner, or a referral for ultrasound, X-ray, CT or MRI through private imaging providers. We will also tell you when a scan is not the right next step.
1–7 days
Personalised results and treatment plan from a private GP consultation
04

Results and next steps

Your GP talks you through what the results mean and agrees the next step with you. Every consultation ends with your treatment plan in writing, and any prescription goes to your own pharmacy.
20 minutes
GP follow-up reminder for ongoing care and progress monitoring
05

Ongoing care and follow-up

Follow-up appointments, progress monitoring and ongoing advice — including saying plainly when something needs in-person or NHS care instead.

Ongoing

How we compare

Time to be seen

Appointment length

Your NHS record in the room

Written treatment plan

Told when a test isn’t needed

Cost

Varies by practice

Typically 10 minutes

Yes, your full record

Not routinely

Usually

Free

Same day

Often 10 to 15 minutes

Usually not

Sometimes charged

Varies by provider

Often a subscription

Questions about our service

How quickly can I be seen?

Same-day access is usually available, from 6am to 10pm, seven days a week. You choose a time that suits you rather than waiting on hold at 8am.

Will I see the same doctor each time?

Yes. Care is led personally by Dr Mohammad Khan, so you are not passed between clinicians. Continuity is the point of a small practice: someone who knows your history and is listening attentively rather than working through a checklist.

Can you see my NHS records?

Yes, with your consent. We can access your Summary Care Record during the consultation, so your current medications, allergies and significant history are in the room. That means fewer questions you have already answered elsewhere, and safer prescribing.

Are you trying to replace my NHS GP?

No. We are not here to replace GPs, only to support them. Your NHS practice remains responsible for your ongoing care, and with your consent we write to them after the consultation. We are useful when you need to be seen sooner, or want more time than a standard appointment allows.

What is included in the appointment?

Twenty unhurried minutes and a comprehensive assessment. A written treatment plan is included, along with any prescription, sick note or referral letter arising from the consultation, at no extra charge.

How much does it cost?

£40 for 20 minutes, self-pay. Membership is optional and never required. Priced for fairness, because we are not here to charge extortionate amounts for access to a doctor.

What does “treatable online” actually mean?

It means the diagnosis can usually be made from your history and photographs, and that treatment can be arranged safely without examining you. Where a condition is not marked treatable online, it is because examination is the diagnosis — listening to a chest, feeling an abdomen, examining an ear or a joint — or because a procedure or device is needed.

Can you prescribe antibiotics?

Yes, where there is a genuine bacterial infection — cellulitis, impetigo, bacterial urine infections, confirmed strep throat. We will also frequently tell you that you do not need one. Most sore throats, coughs, colds and earaches are viral, and an antibiotic gives you the side effects with none of the benefit.

What if the GP cannot help with what I need?

If your problem turns out to be genuinely outside what we can do remotely, the doctor will tell you straight away, point you to the right service, and refund your fee in full. We would rather do that than fill twenty minutes to justify the charge.

What should I do in an emergency?

Call 999 or go to A&E — do not book an online appointment and do not wait for a reply to an email. For urgent problems that are not emergencies, NHS 111 is available 24 hours a day, online or by phone, and can direct you to the right service.

Patient reviews

What our patients say

No reviews published yet.
Ready to see a GP?20 minutes with a GMC-registered doctor. £40, usually same day.
Book a consultation