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Fucibet Cream

Fucibet Cream

A potent steroid combined with an antibiotic, for infected eczema — two weeks maximum, and not for repeat use.

Skin

Betamethasone and fusidic acid cream, Fucicort

Explained by a GMC-registered GP, not a leaflet

Honest about what we can and cannot prescribe remotely

Side effects given the same weight as benefits

Your NHS records in the room, with your consent

Clinically reviewed by Dr Mohammad Khan · Last reviewed

September 5, 2026

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What it is

Fucibet combines two active ingredients:

  • Betamethasone valerate — a potent topical steroid that reduces inflammation and itch
  • Fusidic acid — a topical antibiotic active against Staphylococcus aureus

It exists because eczema and skin infection frequently occur together. Broken, scratched, inflamed skin is readily colonised by staphylococci, and that infection then drives more inflammation — a loop that a steroid alone will not always break.

Both components have a reason to be used briefly. The steroid is potent enough to thin skin over time, and fusidic acid resistance in the UK rose in direct proportion to how freely it was prescribed. Two weeks is the usual ceiling, and it is a genuine limit rather than a formality.

What it is used for

  • Infected eczema or dermatitis — the main use, where there is weeping, golden crusting or a sudden worsening
  • Infected contact dermatitis
  • Other inflammatory skin conditions with secondary bacterial infection

It is not for eczema without infection — that needs a steroid and emollients, without the antibiotic. And it is not for infection without inflammation, which needs the antibiotic alone.

How to take it

  • Apply thinly, twice daily
  • For up to two weeks — and not longer without review
  • Apply to the affected area only, not to unaffected skin around it
  • Keep using emollients alongside, generously and separately

The fingertip unit

One fingertip unit — from the tip of an adult index finger to the first crease — covers about two adult palms of skin. Most people apply far more than they need, and a small tube should last a two-week course comfortably.

Order of application

Emollient first, wait twenty minutes or so, then the steroid — or the other way round, provided they are not applied simultaneously, which dilutes both.

Need this reviewed or prescribed?

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Side effects

Common

  • Stinging or burning on application
  • Local irritation

With prolonged use — the reason for the two-week limit

  • Skin thinning, which can be permanent
  • Stretch marks, which do not reverse
  • Visible small blood vessels
  • Lightening of the skin at the site, and increased hair growth
  • Worsening of any untreated fungal or viral infection
  • Perioral dermatitis or steroid-induced rosacea, if used on the face

From the antibiotic

  • Allergic contact dermatitis to fusidic acid — uncommon, and it looks like the eczema worsening
  • Bacterial resistance with repeated or prolonged use

Not suitable if

  • The skin problem is viral — cold sores, shingles, chickenpox, eczema herpeticum. A potent steroid on a herpes infection can be genuinely dangerous
  • It is fungal — ringworm, tinea. The steroid masks it while it spreads, producing an atypical rash that is then hard to recognise
  • It is acne or rosacea — steroids worsen both
  • You are allergic to fusidic acid or betamethasone
  • It is for a child under one, or for prolonged use in any child, without specific advice

Not for the face, groin or armpits without specific advice — thin skin absorbs potent steroid readily and shows damage first.

The one to recognise urgently

Eczema that suddenly becomes painful, with clusters of small punched-out sores and someone feeling unwell, may be eczema herpeticum — a herpes infection of eczematous skin. That is an emergency, needs antiviral treatment, and a potent steroid will make it worse.

Interactions and monitoring

No significant systemic drug interactions from normal topical use on a limited area.

No routine blood monitoring is needed.

What requires active monitoring is duration and repetition. Two weeks is the ceiling, and repeat prescriptions without review are the mechanism by which people accumulate months of potent steroid and antibiotic on the same patch of skin.

Where infected eczema keeps returning, the question is why the eczema is not controlled between flares — which is nearly always about emollient use, and occasionally about something else entirely.

Can we prescribe this?

Yes, for a defined episode of infected eczema, assessed from good photographs. Weeping, golden-yellow crusting, or eczema that has suddenly and markedly worsened are the features that suggest infection.

What a consultation should establish: that it is genuinely infected rather than simply flaring, that it is not viral or fungal, and that emollients are being used properly — which is where most eczema management actually fails.

What we will not do is issue this on repeat. A potent steroid combined with an antibiotic, used continuously, causes irreversible skin changes and drives fusidic acid resistance. Where eczema needs ongoing potent treatment, that is a dermatology referral rather than a standing prescription.

What needs urgent in-person care: suspected eczema herpeticum — painful clustered punched-out sores with feeling unwell — which is an emergency; spreading infection with fever; or extensive infected eczema needing oral antibiotics.

This page is information, not an offer to supply.

Cost and supply

Fucibet is prescription-only and modestly priced as a generic. On a private prescription it costs somewhat more than the England NHS prescription charge. NHS prescriptions are free in Wales.

What matters more than the tube

Emollients — available cheaply over the counter, and in large quantities on NHS prescription. Used generously and daily, they do more to prevent infected eczema than any short course of Fucibet treats. This is the least glamorous and most effective thing on the page.

Cheaper components

  • Hydrocortisone 1% is over the counter for mild eczema, though it is far milder than betamethasone
  • Antiseptic emollients and bath additives can reduce staphylococcal load without antibiotics

Where paying is justified

A genuine infected flare that needs settling quickly, and a proper review of why flares keep becoming infected — which usually has a fixable answer.

Stopping or switching

Stop at two weeks. Once the infection has settled, step down to a plain steroid of appropriate potency, then to emollients alone. Continuing the antibiotic component beyond the infection serves no purpose and drives resistance.

If it has not worked

  • It was viral — particularly eczema herpeticum, which worsens on steroid
  • It was fungal — the steroid masked and spread it
  • Fusidic acid resistance, which is common enough in the UK to be a realistic explanation
  • Allergy to fusidic acid itself
  • The eczema is simply not controlled, and needs a proper maintenance plan rather than repeated rescue treatment

Alternatives

  • A plain topical steroid plus emollients — for eczema without infection, which is most of it
  • Oral flucloxacillin — for extensive infected eczema
  • Antiseptic emollients or bath additives — to reduce bacterial load without antibiotics
  • Tacrolimus or pimecrolimus — steroid-free, useful for the face and folds

Common questions

How do I know my eczema is infected?

Weeping, golden-yellow crusting, small pustules, increasing pain, or a sudden marked worsening — sometimes with fever or feeling unwell.

Ordinary eczema is itchy, dry and red. Infected eczema is wet, crusted and sore, and the change is usually noticeable.

How long can I use it?

Two weeks maximum without review. Both components have reasons for a short course — the steroid thins skin, the antibiotic drives resistance.

Can I use it on my face?

Not without being told to. Betamethasone is potent and facial skin is thin. Steroid-induced rosacea and perioral dermatitis are genuinely difficult to treat afterwards.

Will it thin my skin?

Not from a two-week course used correctly. Thinning comes from potent steroids used continuously for months, or on thin skin.

Being too frightened to use enough is its own problem — undertreated eczema stays itchy, gets scratched, and becomes infected again.

Why can I not have it on repeat?

Because continuous use causes skin changes that do not reverse, and because repeated fusidic acid drives resistance. If you need it often, the real problem is that the eczema is not controlled between flares — and that is worth solving properly.

Do I still need my moisturiser?

Yes, and it matters more than the steroid over a year. Emollients used generously every day are what keep the skin barrier intact, which is what stops the flares that become infected.

My eczema suddenly became very painful with little blisters. What is that?

Seek advice today. Painful clustered punched-out sores on eczematous skin, particularly with feeling unwell, can be eczema herpeticum — a herpes infection needing antiviral treatment. A potent steroid makes it worse, so this is one to act on rather than treat.

Dr Mohammad Zubair Khan, GMC-registered private GP and founder of Cheshire Clinics

Clinically reviewed by Dr Mohammad Zubair Khan, GMC 7563469

Last reviewed

September 5, 2026

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How we compare

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Questions about our service

How quickly can I be seen?

Same-day access is usually available, from 6am to 10pm, seven days a week. You choose a time that suits you rather than waiting on hold at 8am.

Will I see the same doctor each time?

Yes. Care is led personally by Dr Mohammad Khan, so you are not passed between clinicians. Continuity is the point of a small practice: someone who knows your history and is listening attentively rather than working through a checklist.

Can you see my NHS records?

Yes, with your consent. We can access your Summary Care Record during the consultation, so your current medications, allergies and significant history are in the room. That means fewer questions you have already answered elsewhere, and safer prescribing.

Are you trying to replace my NHS GP?

No. We are not here to replace GPs, only to support them. Your NHS practice remains responsible for your ongoing care, and with your consent we write to them after the consultation. We are useful when you need to be seen sooner, or want more time than a standard appointment allows.

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Twenty unhurried minutes and a comprehensive assessment. A written treatment plan is included, along with any prescription, sick note or referral letter arising from the consultation, at no extra charge.

How much does it cost?

£40 for 20 minutes, self-pay. Membership is optional and never required. Priced for fairness, because we are not here to charge extortionate amounts for access to a doctor.

What does “treatable online” actually mean?

It means the diagnosis can usually be made from your history and photographs, and that treatment can be arranged safely without examining you. Where a condition is not marked treatable online, it is because examination is the diagnosis — listening to a chest, feeling an abdomen, examining an ear or a joint — or because a procedure or device is needed.

Can you prescribe antibiotics?

Yes, where there is a genuine bacterial infection — cellulitis, impetigo, bacterial urine infections, confirmed strep throat. We will also frequently tell you that you do not need one. Most sore throats, coughs, colds and earaches are viral, and an antibiotic gives you the side effects with none of the benefit.

What if the GP cannot help with what I need?

If your problem turns out to be genuinely outside what we can do remotely, the doctor will tell you straight away, point you to the right service, and refund your fee in full. We would rather do that than fill twenty minutes to justify the charge.

What should I do in an emergency?

Call 999 or go to A&E — do not book an online appointment and do not wait for a reply to an email. For urgent problems that are not emergencies, NHS 111 is available 24 hours a day, online or by phone, and can direct you to the right service.

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