Not prescribed online

Codeine

A weak opioid with unpredictable effect and a real dependence risk. We do not prescribe it remotely, and this page explains why.

Pain & Inflammation

Co-codamol, codeine phosphate, opioid painkiller

Explained by a GMC-registered GP, not a leaflet

Honest about what we can and cannot prescribe remotely

Side effects given the same weight as benefits

Your NHS records in the room, with your consent

Clinically reviewed by Dr Mohammad Khan · Last reviewed

August 30, 2026

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A 20-minute appointment with a GMC-registered GP for £40. Same-day appointments are usually available, 6am to 10pm, seven days a week.

Private GP care led personally by Dr Mohammad Zubair Khan, GMC 7563469.

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Same-Day Appointments
Sick Notes
Private Prescriptions
Blood Tests
Menopause & HRT
Weight Management
Mental Health
Specialist Referrals
Same-Day Appointments
Sick Notes
Private Prescriptions
Blood Tests
Menopause & HRT
Weight Management
Mental Health
Specialist Referrals

What it is

Codeine is a weak opioid analgesic. It is a prodrug — it has little effect until the liver converts it into morphine, which does the actual work.

That conversion is where the unpredictability comes from. It depends on an enzyme, CYP2D6, whose activity varies widely between individuals:

  • Around 5 to 10% of people of European ancestry convert almost none of it — codeine simply does not work for them, and no dose increase helps
  • A smaller group are ultra-rapid metabolisers, converting far more than expected, and can experience dangerous opioid effects at ordinary doses

Co-codamol is codeine combined with paracetamol in a single tablet.

What it is used for

  • Moderate pain not controlled by paracetamol or an NSAID
  • Dry cough, in some preparations
  • Diarrhoea, occasionally

Current UK guidance has moved substantially away from opioids for chronic non-cancer pain, because the evidence for long-term benefit is weak while the evidence of harm — dependence, tolerance, and pain that worsens on treatment — is strong.

NICE guidance on chronic primary pain does not recommend opioids at all.

How to take it

Where a clinician who has examined you prescribes codeine, take it exactly as directed, for the shortest period possible.

  • Low-dose co-codamol is available from pharmacies for short-term use only — a maximum of three days
  • Constipation is near-universal and should be anticipated with a laxative rather than treated later
  • Never exceed the paracetamol maximum when taking co-codamol, and never add separate paracetamol on top

Do not drive if it makes you drowsy. It is an offence to drive while impaired, and codeine is covered by drug-driving law.

Need this reviewed or prescribed?

Book a consultation

Side effects

Common

  • Constipation — affects almost everyone and does not improve with time
  • Drowsiness, dizziness, nausea
  • Dry mouth

Serious

  • Respiratory depression — dangerously slowed breathing, particularly with alcohol, sedatives or in ultra-rapid metabolisers
  • Dependence and tolerance, which can develop within weeks
  • Medication overuse headache, where codeine is a frequent culprit
  • Opioid-induced hyperalgesia — pain that worsens because of the treatment

Not suitable if

  • You are under 18 and have had tonsils or adenoids removed for sleep apnoea — contraindicated after reported deaths
  • You are under 12 — codeine is contraindicated in children
  • You are breastfeeding — an ultra-rapid metaboliser can pass dangerous amounts to the infant
  • You have significant respiratory disease
  • You have a history of opioid dependence
  • You take sedatives, or drink alcohol regularly

Interactions and monitoring

  • Alcohol, benzodiazepines, z-drugs and gabapentinoids — combined sedation and respiratory depression. This combination causes deaths
  • Other opioids, including in cough remedies
  • Paracetamol-containing products alongside co-codamol — a real overdose route
  • Fluoxetine, paroxetine and bupropion — block the enzyme that activates codeine, so it stops working

Anyone taking codeine regularly needs proper review of whether it is still helping, which is a face-to-face conversation about function rather than a pain score.

Can we prescribe this?

No. Not in any circumstances, and not as a one-off.

We do not prescribe codeine or any other opioid remotely. That applies to first requests, to repeat requests, to people who have taken it safely for years, and to people in genuine pain.

The reasons are not administrative:

  • Pain severe enough to need an opioid needs examining, and we cannot examine you over video
  • Dependence develops quietly, and a remote service has no way to see the pattern building
  • Opioid requests are the commonest target of misrepresentation to online services, and no remote assessment reliably detects that

This page exists so that the answer is clear before you book rather than after you have paid. If codeine is what you are looking for, we are not the right service, and we would rather say so here.

What we can do is assess the pain properly, treat what is causing it, use the analgesics that are safe to prescribe remotely, and refer where that is what is needed.

Cost and supply

Codeine is inexpensive as a drug. It is a controlled drug under UK law, with prescribing restrictions that exist for good reason.

Low-dose co-codamol can be bought from a pharmacy after speaking to the pharmacist, licensed for three days only. Buying it repeatedly from different pharmacies is a recognised pattern of dependence, and pharmacists are trained to notice it — not to catch people out, but because it is treatable.

Codeine bought online without a prescription may be counterfeit and may not be codeine at all. Tablets sold as opioids have contained synthetic opioids many times stronger, and people have died.

Stopping or switching

Do not stop abruptly after regular use

Opioid withdrawal is unpleasant — anxiety, sweating, aching, insomnia, diarrhoea and agitation. It is not dangerous in the way alcohol withdrawal is, but it is enough to drive people straight back onto the drug.

Reduction should be gradual and supported, typically by around 10% of the dose every one to two weeks, slower at the end. Many people find their pain no worse, and their function better, once off it.

Getting help

Needing codeine to feel normal, taking more than prescribed, or running out early are signs of dependence, not of weakness. Your NHS GP can help, and local drug and alcohol services accept self-referral. This is common and treatable, and asking is the hard part.

Common questions

Will you prescribe codeine if I have taken it for years?

No. Long-standing use is a reason for a proper face-to-face review, not for a remote prescription. Your NHS GP holds your record and can see the full picture.

I have run out and my GP is closed. Can you help?

Not with an opioid. Contact NHS 111, who can arrange urgent supply of regular medication out of hours. That route exists precisely for this.

Why does codeine do nothing for me?

Because around one in ten people cannot convert it to morphine. It is genetic, not imagined, and taking more will not help — a different class of painkiller is needed.

Is it addictive?

Yes. Dependence can develop within weeks of regular use, often in people who never expected it and who took it exactly as prescribed.

What can you offer instead?

A proper assessment of what is causing the pain, treatment aimed at the cause, non-opioid analgesia including topical and neuropathic options, and referral where needed. For many chronic pain conditions that is better care than an opioid, not a lesser substitute.

Dr Mohammad Zubair Khan, GMC-registered private GP and founder of Cheshire Clinics

Clinically reviewed by Dr Mohammad Zubair Khan, GMC 7563469

Last reviewed

August 30, 2026

How it works

What happens when you book

£40 for a 20-minute appointment with a GMC-registered GP, 6am to 10pm, seven days a week. Membership is optional and never required.
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01

Book your appointment

Pick a time that suits you — 6am to 10pm, seven days a week, including weekends and bank holidays. £40 for 20 minutes, self-pay, with no insurance to arrange.
5–10 minutes
Online video consultation with a GMC-registered private GP
02

Meet your GP

A 20-minute video or phone consultation with a GMC-registered GP — long enough for a proper conversation about your symptoms, your history and what matters to you.
20 minutes
Diagnostic testing plan including blood test panel, ECG and urine screening
03

Tests and referrals, if you need them

Where testing will actually answer the question, we arrange it — blood tests and health screening through our laboratory partner, or a referral for ultrasound, X-ray, CT or MRI through private imaging providers. We will also tell you when a scan is not the right next step.
1–7 days
Personalised results and treatment plan from a private GP consultation
04

Results and next steps

Your GP talks you through what the results mean and agrees the next step with you. Every consultation ends with your treatment plan in writing, and any prescription goes to your own pharmacy.
20 minutes
GP follow-up reminder for ongoing care and progress monitoring
05

Ongoing care and follow-up

Follow-up appointments, progress monitoring and ongoing advice — including saying plainly when something needs in-person or NHS care instead.

Ongoing

How we compare

Time to be seen

Appointment length

Your NHS record in the room

Written treatment plan

Told when a test isn’t needed

Cost

Varies by practice

Typically 10 minutes

Yes, your full record

Not routinely

Usually

Free

Same day

Often 10 to 15 minutes

Usually not

Sometimes charged

Varies by provider

Often a subscription

Questions about our service

How quickly can I be seen?

Same-day access is usually available, from 6am to 10pm, seven days a week. You choose a time that suits you rather than waiting on hold at 8am.

Will I see the same doctor each time?

Yes. Care is led personally by Dr Mohammad Khan, so you are not passed between clinicians. Continuity is the point of a small practice: someone who knows your history and is listening attentively rather than working through a checklist.

Can you see my NHS records?

Yes, with your consent. We can access your Summary Care Record during the consultation, so your current medications, allergies and significant history are in the room. That means fewer questions you have already answered elsewhere, and safer prescribing.

Are you trying to replace my NHS GP?

No. We are not here to replace GPs, only to support them. Your NHS practice remains responsible for your ongoing care, and with your consent we write to them after the consultation. We are useful when you need to be seen sooner, or want more time than a standard appointment allows.

What is included in the appointment?

Twenty unhurried minutes and a comprehensive assessment. A written treatment plan is included, along with any prescription, sick note or referral letter arising from the consultation, at no extra charge.

How much does it cost?

£40 for 20 minutes, self-pay. Membership is optional and never required. Priced for fairness, because we are not here to charge extortionate amounts for access to a doctor.

What does “treatable online” actually mean?

It means the diagnosis can usually be made from your history and photographs, and that treatment can be arranged safely without examining you. Where a condition is not marked treatable online, it is because examination is the diagnosis — listening to a chest, feeling an abdomen, examining an ear or a joint — or because a procedure or device is needed.

Can you prescribe antibiotics?

Yes, where there is a genuine bacterial infection — cellulitis, impetigo, bacterial urine infections, confirmed strep throat. We will also frequently tell you that you do not need one. Most sore throats, coughs, colds and earaches are viral, and an antibiotic gives you the side effects with none of the benefit.

What if the GP cannot help with what I need?

If your problem turns out to be genuinely outside what we can do remotely, the doctor will tell you straight away, point you to the right service, and refund your fee in full. We would rather do that than fill twenty minutes to justify the charge.

What should I do in an emergency?

Call 999 or go to A&E — do not book an online appointment and do not wait for a reply to an email. For urgent problems that are not emergencies, NHS 111 is available 24 hours a day, online or by phone, and can direct you to the right service.

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