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Gallstones

Most gallstones never cause trouble. The ones that do have a characteristic pattern.

£40 · 20 minutes

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6am to 10pm, seven days

Assessed and treated by a GMC-registered GP

Prescriptions, sick notes and referral letters included

A written treatment plan after every appointment

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Clinically reviewed by Dr Mohammad Khan · Last reviewed

August 23, 2026

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Private GP care led personally by Dr Mohammad Zubair Khan, GMC 7563469.

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Same-Day Appointments
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Same-Day Appointments
Sick Notes
Private Prescriptions
Blood Tests
Menopause & HRT
Weight Management
Mental Health
Specialist Referrals

Overview

Gallstones form in the gallbladder, a small sac under the liver that stores bile. They are very common — around one adult in ten has them — and the great majority never cause a single symptom.

That last point matters more than it sounds. Silent gallstones found incidentally on a scan need no treatment and no operation. Most people who have them will go their whole lives without knowing. Being told you have gallstones is not, on its own, being told you need surgery.

What changes things is symptoms — and when they come, the pattern is distinctive:

Biliary colic is a severe, constant pain in the upper abdomen, often to the right, typically starting an hour or two after a fatty meal and lasting from thirty minutes to several hours. It frequently radiates to the right shoulder blade, and it comes with nausea and vomiting. Despite the name, it is not colicky — it builds, plateaus, and eases, rather than coming in waves. Being told to expect waves is one reason people misidentify it.

Three things needing urgent attention, because gallstone complications are where the real risk sits:

  • Pain lasting more than six hours, with fever — infection of the gallbladder
  • Jaundice with pain and fever — infection in the bile ducts, which can become life-threatening quickly
  • Severe pain boring through to the back with vomiting — possible gallstone pancreatitis

And one thing we would rather say than have you discover: rapid weight loss increases gallstone formation — including weight loss on GLP-1 weight-management medicines. It is a real and well-documented effect, and we would rather you knew about it in advance.

Common symptoms

Most often, nothing

The majority of gallstones are silent, cause no symptoms and are found incidentally on a scan requested for something else. That is the normal outcome.

Biliary colic — the classic attack

  • Severe, constant pain in the upper abdomen, usually right-sided or central
  • Lasting 30 minutes to several hours, then easing completely
  • Often starting one to two hours after eating, particularly a fatty meal
  • Radiating to the right shoulder blade or between the shoulders — a highly characteristic feature
  • Nausea, and often vomiting
  • Restlessness — people move about trying to get comfortable, unlike peritonitis, where any movement is avoided
  • Frequently coming on at night

Between attacks you feel entirely normal, which is why the diagnosis is often delayed — by the time an appointment comes round, there is nothing to find.

Other symptoms attributed to gallstones

Bloating, wind, indigestion and fatty food intolerance are commonly blamed on gallstones. They are just as common in people without them, and removing the gallbladder frequently does not resolve them — which is worth knowing before an operation is agreed on that basis alone.

Acute cholecystitis — infection of the gallbladder

  • Pain lasting more than six hours and not settling
  • Fever and shivering
  • Marked tenderness in the right upper abdomen
  • Feeling generally unwell

The complications that are emergencies

  • Ascending cholangitisjaundice, fever and pain together. Infection within the bile ducts, which can progress to sepsis rapidly. Yellow skin or eyes with pain and fever means hospital now
  • Gallstone pancreatitis — severe upper abdominal pain boring through to the back, with vomiting, often eased slightly by leaning forward
  • Obstructive jaundice — yellow skin and eyes, dark urine and pale stools, and itching. Note that painless jaundice needs urgent assessment for a different reason: it can indicate pancreatic disease

Causes and risk factors

How they form

Bile contains cholesterol, bile salts and bilirubin. When the balance shifts, or the gallbladder empties sluggishly, crystals form and grow into stones. Most are cholesterol stones; pigment stones occur where red cells are broken down excessively.

Symptoms happen when a stone blocks the outlet, and the gallbladder contracts against the obstruction — which is why an attack follows a fatty meal, the trigger for that contraction.

What increases the risk

  • Female sex — roughly twice the risk, largely through oestrogen
  • Age — rising steadily through adult life
  • Pregnancy, and the combined pill or HRT
  • Excess weight, particularly around the abdomen
  • Rapid weight loss — covered below, because it is important and increasingly relevant
  • Family history
  • Diabetes, and raised triglycerides
  • Crohn's disease, or surgery involving the terminal ileum
  • Certain ethnic backgrounds, including South Asian and Hispanic populations, and notably high rates in some Indigenous American groups
  • Some medications, including octreotide and ceftriaxone

A note on the old "fair, fat, forty, female, fertile" mnemonic: it is both inaccurate and unkind, and it is not how anyone should be assessed. Age, sex, pregnancy and weight change are genuine factors; the phrasing is a relic.

Rapid weight loss — including on weight-loss injections

Losing weight quickly substantially increases the chance of forming gallstones. When fat is broken down rapidly, more cholesterol enters the bile, and a gallbladder emptying less often on a reduced food intake gives stones time to form.

This applies to very low calorie diets, to bariatric surgery, and to GLP-1 weight-management medicines. It is a recognised effect, it appears in the safety information, and it is one of the reasons we discuss the risks properly rather than simply issuing a prescription. Losing weight at a steadier pace, and not skipping meals entirely, reduces it.

What does not cause them

  • Eating fatty food does not create gallstones — it triggers attacks in someone who already has them
  • Stress
  • Skipping meals is not protective and may be the opposite — a gallbladder that is not emptying regularly is a gallbladder in which stones form more easily

How it is diagnosed

Gallstones are diagnosed by ultrasound, and the history is often close to diagnostic on its own — which makes this well suited to a remote consultation, with the scan arranged afterwards.

What we establish

  • The pattern of pain — where, how long, what it radiates to, what brings it on. Severe pain lasting hours after a fatty meal, going to the right shoulder blade, is close to diagnostic
  • How long attacks last, and whether you are completely well between them
  • Any fever, jaundice, dark urine or pale stools — asked in every case, because these change the urgency entirely
  • Whether you have lost weight rapidly, and how — including any weight-loss medication
  • Alcohol history, relevant to pancreatitis and liver disease
  • Medication, family history and previous abdominal surgery

Tests we arrange

  • Abdominal ultrasound — the test of choice, and highly accurate for stones in the gallbladder. Best done fasted, so the gallbladder is distended and visible. We can arrange this
  • Liver function tests — which look for a stone that has moved into the bile duct. Note that normal liver tests do not exclude gallstones, and are usually normal in simple biliary colic
  • Amylase or lipase where pancreatitis is a possibility
  • Full blood count and inflammatory markers where infection is suspected

What ultrasound is less good at

Stones in the bile duct are easily missed on standard ultrasound. Where liver tests are abnormal or the duct looks dilated, an MRCP — a specialised MRI — is the next step, and we refer for it.

What we cannot do remotely

We cannot examine your abdomen. Pain lasting more than a few hours, fever, or jaundice needs assessment in person the same day, and we will say so directly rather than arranging an outpatient scan for someone who needs a hospital.

What else it might be

  • Indigestion, peptic ulcer disease and H. pylori infection — all common and all treatable
  • Cardiac pain — a heart attack can present as upper abdominal pain with nausea, particularly in women and people with diabetes
  • Kidney stones, right-sided
  • Pancreatitis
  • Right lower lobe pneumonia, which refers pain to the upper abdomen
  • IBS — for the bloating and wind, though not for the severe episodic pain

How we treat it online

1. Silent stones: no treatment

Gallstones found by accident, causing no symptoms, do not need an operation. The risk of developing symptoms is modest each year, and surgery carries its own risks. Watchful waiting is correct, and being told so clearly saves a lot of unnecessary worry — and sometimes an unnecessary operation.

2. Managing an attack

  • Strong pain relief — an anti-inflammatory such as diclofenac is particularly effective for biliary colic, where appropriate, and often better than an opioid
  • Anti-sickness medication
  • Fluids, and nothing by mouth while the pain is severe
  • An attack lasting more than six hours, or with fever, is no longer simple biliary colic and needs assessing in person

3. Reducing attacks while you wait

A lower-fat diet reduces how often attacks happen, because less fat means less gallbladder contraction. It does not dissolve the stones, and it is a holding measure rather than a treatment. Regular meals matter too — long fasting periods allow bile to sit and concentrate.

4. Surgery — the definitive treatment

Laparoscopic cholecystectomy: keyhole removal of the gallbladder, usually a day case, with a return to normal activity in one to two weeks.

  • Offered to people with symptomatic gallstones, because attacks recur and complications develop in a meaningful proportion of people who wait
  • You do not need a gallbladder. Bile flows continuously from the liver into the bowel instead, and most people notice no difference
  • We refer, and we can provide a specialist referral letter

5. The after-effect nobody mentions

Some people develop persistent loose, urgent stools after gallbladder removal — typically first thing in the morning, and often labelled "IBS" afterwards. It is usually bile acid malabsorption, it is diagnosable with a SeHCAT scan, and it responds dramatically to a bile acid binder such as colestyramine. A great many people put up with it for years without knowing it is treatable. If that describes you, come and say so.

6. Where medication has a role

Ursodeoxycholic acid can dissolve small cholesterol stones, but takes many months, works in a minority, and stones usually return after stopping. It is reserved for people who cannot have surgery, and we would be honest about its limits rather than offering it as an easy alternative.

7. What we will not do

  • Recommend surgery for silent gallstones found incidentally
  • Manage pain lasting more than a few hours, fever or jaundice remotely
  • Attribute upper abdominal pain to gallstones without considering the heart
  • Support "gallbladder flushes" — see below
  • Prescribe weight-loss medication without discussing the gallstone risk
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Important

When to seek urgent help

Call 999 or go to A&E immediately for:

  • Yellowing of the skin or eyes with pain and fever — this suggests infection in the bile ducts, which can become life-threatening within hours. Do not wait for a routine appointment
  • Severe upper abdominal pain boring through to the back with vomiting — possible gallstone pancreatitis
  • Severe abdominal pain with a rigid abdomen
  • Confusion, drowsiness or collapse with abdominal pain and fever — possible sepsis
  • Chest pain, or upper abdominal pain with sweating, breathlessness or pain into the jaw or arm — a heart attack can present exactly this way, and is missed more often in women and in people with diabetes

Seek same-day medical assessment for:

  • Pain lasting more than six hours, or not settling with pain relief
  • Fever or shivering with upper abdominal pain
  • Dark urine and pale stools, with or without yellowing
  • Persistent vomiting and inability to keep fluids down
  • Increasing pain despite treatment

Arrange an urgent appointment for:

  • Painless jaundice — yellowing without pain, which needs urgent assessment for a different reason
  • Unexplained weight loss with abdominal pain
  • Recurrent attacks that are becoming more frequent or more severe

Book a routine consultation for:

  • Episodes of severe upper abdominal pain after eating, lasting from half an hour to several hours
  • Gallstones found on a scan, with nobody having explained whether anything needs doing
  • Discussing whether surgery is right for you
  • Loose, urgent stools since having your gallbladder removed — which is usually bile acid malabsorption and is very treatable
  • Starting or taking weight-loss medication and wanting to understand the gallstone risk

Prevention and self-care

Reducing attacks

  • Lower-fat eating — the most effective everyday measure. Fatty, fried and creamy foods, and large rich meals, are the common triggers
  • Smaller, more regular meals. Long gaps allow bile to concentrate; regular eating keeps the gallbladder emptying
  • Keep a note of what preceded attacks — triggers are quite individual
  • Stay well hydrated

Reducing the chance of forming stones

  • Lose weight gradually rather than rapidly. Around 0.5–1kg a week; crash dieting is one of the strongest risk factors there is
  • Do not skip meals while dieting. Counter-intuitive, but a gallbladder that does not empty is where stones form
  • Regular physical activity, which independently reduces risk
  • A diet with adequate fibre, wholegrains, fruit, vegetables and healthy fats; less refined carbohydrate and sugar

If you are taking weight-loss medication

Worth stating plainly: rapid weight loss on GLP-1 medication increases gallstone risk. It does not mean you should not take it — the benefits of treating obesity are substantial — but it does mean:

  • Aim for steady rather than maximal weight loss
  • Keep eating regular meals, even if smaller
  • Know the symptoms of biliary colic before they happen, and tell us if you get severe upper abdominal pain lasting more than half an hour
  • Report jaundice, fever or persistent pain immediately

The "gallbladder flush" — a clear debunk

The olive oil and lemon juice "liver flush" does not remove gallstones. The soft green-brown objects passed afterwards have been chemically analysed repeatedly: they are soap — the oil saponified by digestive juices in the gut. They contain no cholesterol and no bilirubin, and they form in a bucket if you mix the ingredients outside the body.

Beyond being useless, it is not harmless: a large fat load in someone with gallstones can precipitate a genuine attack, or dislodge a stone into the bile duct. People have needed emergency surgery after doing one.

Supplements and alternative remedies

No supplement dissolves gallstones. Milk thistle, apple cider vinegar and various herbal preparations are widely marketed on that claim with nothing behind it. If the pain is troublesome enough to be looking for remedies, it is troublesome enough to be assessed properly.

Do not wait too long

Once attacks have started, they usually recur, and a proportion of people go on to develop cholecystitis, jaundice or pancreatitis — which turn a planned day-case operation into an emergency admission. Having it dealt with electively is considerably safer than having it dealt with urgently.

NHS or private

Gallstones that cause no symptoms usually need no treatment at all — they are common, frequently found incidentally on a scan done for something else, and most never cause trouble. Surgery for silent gallstones is not routinely recommended.

NHS care covers everything free — ultrasound, blood tests, and laparoscopic cholecystectomy, which is the definitive treatment where stones are causing symptoms.

What costs nothing and genuinely helps between episodes is dietary fat reduction, since fatty meals trigger gallbladder contraction and therefore pain.

Where money is wasted: gallbladder “flushes” and cleanses sold online, which do not dissolve stones — the objects people report passing are saponified oil, not gallstones. Ursodeoxycholic acid dissolution therapy works poorly for most stones and is rarely used.

Where a private consultation is genuinely worth paying for is a prompt ultrasound and blood tests when pain is recurring, and a referral — because the argument for surgery strengthens with each episode, and complications are what should be avoided rather than endured.

Private cholecystectomy can shorten a long wait, which is a legitimate reason to pay when attacks are frequent.

What needs emergency assessment: pain lasting more than a few hours with fever; jaundice — yellow eyes or skin, dark urine, pale stools, which suggests a stone blocking the bile duct; or severe pain radiating to the back with vomiting, which can indicate pancreatitis.

Evidence and guidelines

NICE CG188, Gallstone disease: diagnosis and management, is the governing guideline. It recommends ultrasound as first-line imaging and laparoscopic cholecystectomy for people with symptomatic gallstones.

CG188 recommends against routine surgery for asymptomatic gallbladder stones found incidentally — the basis for the point above.

CG188 covers management of common bile duct stones, including ERCP and bile duct clearance, and recommends cholecystectomy for people with acute cholecystitis, biliary colic or gallstone pancreatitis.

CG188 recommends offering advice on reducing dietary fat for symptom control while awaiting treatment.

NICE CG188 and CKS set out the complications requiring urgent assessment — acute cholecystitis, cholangitis, obstructive jaundice and gallstone pancreatitis — which underpin the emergency features listed.

Common questions

I've been told I have gallstones but I feel fine. Do I need an operation?

No. Silent gallstones found incidentally on a scan need no treatment. Only a minority go on to cause symptoms, and surgery carries its own risks, so watchful waiting is the correct approach. Being told you have gallstones is not the same as being told you need them removed.

What does a gallstone attack actually feel like?

Severe, constant pain in the upper abdomen — usually on the right — typically starting one to two hours after a fatty meal, lasting from thirty minutes to several hours, often radiating to the right shoulder blade, with nausea and vomiting. Despite being called "biliary colic", it does not come in waves. It builds, plateaus and then eases, and you feel entirely normal in between.

Can I avoid surgery with diet?

A lower-fat diet genuinely reduces how often attacks happen, and regular meals help. But it does not dissolve the stones, and once attacks have started they usually keep coming. Diet is a holding measure. The risk of waiting is that a planned day-case operation becomes an emergency admission with cholecystitis or pancreatitis.

Does the olive oil and lemon juice flush work?

No. The green-brown objects passed afterwards have been analysed many times: they are soap, formed when the oil reacts with digestive juices in the gut. They contain no cholesterol or bilirubin, and the same objects form in a jar outside the body. Worse, a large fat load in someone with gallstones can trigger a genuine attack or dislodge a stone — people have ended up in emergency surgery after trying one.

Can I live without a gallbladder?

Yes, entirely normally. The gallbladder stores and concentrates bile, but the liver keeps producing it and it simply flows continuously into the bowel instead. Most people notice no difference and can eat normally, though it is sensible to reintroduce fatty foods gradually in the first few weeks.

I keep getting diarrhoea since my gallbladder was removed.

Common, treatable, and frequently mislabelled as IBS. It is usually bile acid malabsorption — bile now flowing continuously into the bowel rather than in controlled amounts — and it responds dramatically to a bile acid binder such as colestyramine. A great many people put up with this for years without being told it has a name and a treatment.

Could my weight-loss injection have caused this?

It may have contributed, and we would rather be straightforward about it. Rapid weight loss — from any cause, including GLP-1 medications like tirzepatide and semaglutide — increases gallstone formation, because more cholesterol enters the bile and the gallbladder empties less often. It is a recognised effect. It does not mean stopping treatment is automatically right, but it does mean losing weight steadily, not skipping meals entirely, and telling us about any severe upper abdominal pain.

My liver tests were normal, so it can't be gallstones?

Not so — liver function tests are usually normal in straightforward biliary colic and do not exclude gallstones. They become abnormal when a stone moves into the bile duct. Ultrasound is the test that finds stones in the gallbladder, and it should be done fasted.

Why does it hurt in my shoulder?

Referred pain. The gallbladder and the skin over the right shoulder blade share nerve supply through the diaphragm, so the brain interprets the signal as coming from the shoulder. It is one of the most characteristic features of biliary pain and is genuinely useful in making the diagnosis.

Dr Mohammad Zubair Khan, GMC-registered private GP and founder of Cheshire Clinics
Clinically reviewed by Dr Mohammad Zubair Khan, GMC 7563469
Last reviewed

August 23, 2026

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What happens when you book

£40 for a 20-minute appointment with a GMC-registered GP, 6am to 10pm, seven days a week. Membership is optional and never required.
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Pick a time that suits you — 6am to 10pm, seven days a week, including weekends and bank holidays. £40 for 20 minutes, self-pay, with no insurance to arrange.
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A 20-minute video or phone consultation with a GMC-registered GP — long enough for a proper conversation about your symptoms, your history and what matters to you.
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Where testing will actually answer the question, we arrange it — blood tests and health screening through our laboratory partner, or a referral for ultrasound, X-ray, CT or MRI through private imaging providers. We will also tell you when a scan is not the right next step.
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Your GP talks you through what the results mean and agrees the next step with you. Every consultation ends with your treatment plan in writing, and any prescription goes to your own pharmacy.
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Ongoing care and follow-up

Follow-up appointments, progress monitoring and ongoing advice — including saying plainly when something needs in-person or NHS care instead.

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How we compare

Time to be seen

Appointment length

Your NHS record in the room

Written treatment plan

Told when a test isn’t needed

Cost

Varies by practice

Typically 10 minutes

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Usually

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Questions about our service

How quickly can I be seen?

Same-day access is usually available, from 6am to 10pm, seven days a week. You choose a time that suits you rather than waiting on hold at 8am.

Will I see the same doctor each time?

Yes. Care is led personally by Dr Mohammad Khan, so you are not passed between clinicians. Continuity is the point of a small practice: someone who knows your history and is listening attentively rather than working through a checklist.

Can you see my NHS records?

Yes, with your consent. We can access your Summary Care Record during the consultation, so your current medications, allergies and significant history are in the room. That means fewer questions you have already answered elsewhere, and safer prescribing.

Are you trying to replace my NHS GP?

No. We are not here to replace GPs, only to support them. Your NHS practice remains responsible for your ongoing care, and with your consent we write to them after the consultation. We are useful when you need to be seen sooner, or want more time than a standard appointment allows.

What is included in the appointment?

Twenty unhurried minutes and a comprehensive assessment. A written treatment plan is included, along with any prescription, sick note or referral letter arising from the consultation, at no extra charge.

How much does it cost?

£40 for 20 minutes, self-pay. Membership is optional and never required. Priced for fairness, because we are not here to charge extortionate amounts for access to a doctor.

What does “treatable online” actually mean?

It means the diagnosis can usually be made from your history and photographs, and that treatment can be arranged safely without examining you. Where a condition is not marked treatable online, it is because examination is the diagnosis — listening to a chest, feeling an abdomen, examining an ear or a joint — or because a procedure or device is needed.

Can you prescribe antibiotics?

Yes, where there is a genuine bacterial infection — cellulitis, impetigo, bacterial urine infections, confirmed strep throat. We will also frequently tell you that you do not need one. Most sore throats, coughs, colds and earaches are viral, and an antibiotic gives you the side effects with none of the benefit.

What if the GP cannot help with what I need?

If your problem turns out to be genuinely outside what we can do remotely, the doctor will tell you straight away, point you to the right service, and refund your fee in full. We would rather do that than fill twenty minutes to justify the charge.

What should I do in an emergency?

Call 999 or go to A&E — do not book an online appointment and do not wait for a reply to an email. For urgent problems that are not emergencies, NHS 111 is available 24 hours a day, online or by phone, and can direct you to the right service.

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