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Tired All The Time Blood Test

Tired All The Time Blood Test

A panel built specifically for unexplained tiredness, covering the treatable causes that routine testing often misses.

Quoted after consultation

Results usually within 2 working days

Blood sample

Referred by a GMC-registered GP, results reviewed by the same doctor

Taken at a partner site near you

Results explained in plain English, not just a number

Your NHS records in the room, with your consent

Clinically reviewed by Dr Mohammad Khan · Last reviewed

August 23, 2026

Book a consultation

A 20-minute appointment with a GMC-registered GP for £40. Same-day appointments are usually available, 6am to 10pm, seven days a week.

Private GP care led personally by Dr Mohammad Zubair Khan, GMC 7563469.

Why patients choose Cheshire Clinics

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Care led personally by Dr Khan

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RCGP-trained

Attentive, unhurried care that listens properly

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Registered with the Care Quality Commission

Same-Day Appointments
Sick Notes
Private Prescriptions
Blood Tests
Menopause & HRT
Weight Management
Mental Health
Specialist Referrals
Same-Day Appointments
Sick Notes
Private Prescriptions
Blood Tests
Menopause & HRT
Weight Management
Mental Health
Specialist Referrals

Overview

"Tired all the time" is one of the commonest reasons people see a GP, and one of the most frequently dismissed. It gets attributed to stress, to age, to having young children, to working too hard — and sometimes that is right.

Often it is not. Iron deficiency, an underactive thyroid, B12 deficiency, vitamin D deficiency and early diabetes all present as fatigue long before anything else, and all are straightforward to treat once identified.

This panel tests for them together, because they overlap and because testing one at a time wastes months.

What this test measures

The treatable causes of fatigue, in a single sample. It is deliberately broader than the tests usually run for tiredness, and deliberately narrower than a full health check — it is built for one question.

Why you might need it

Persistent tiredness that sleep does not fix. Difficulty concentrating or brain fog. Breathlessness on stairs you used to manage. Feeling cold when others do not. Hair thinning or shedding. Low mood without an obvious cause.

It is also worth considering if you have already been tested elsewhere, told everything was normal, and still feel unwell — basic testing often covers only a fraction of what is on this panel.

What's included

Thyroid — full panel

  • TSH, free T4 and free T3
  • Thyroid antibodies (anti-Tg and anti-TPO), which identify autoimmune thyroid disease that a TSH alone will not show

Iron and blood

  • Full blood count
  • Ferritin, iron, transferrin, transferrin saturation and total iron binding capacity

Vitamins

  • Vitamin B12 and folate
  • Vitamin D

Blood sugar

  • Glucose and HbA1c
  • Insulin and C-peptide, which show insulin resistance years before blood sugar itself becomes abnormal

Organ function and inflammation

  • Kidney function including cystatin C and magnesium
  • C-reactive protein
  • Calcium, albumin and alkaline phosphatase

Ready to arrange this test?

Book a consultation

How the referral works

Partner site:

Randox Health

1. Consultation first

Twenty minutes to take a proper fatigue history. This matters more than it sounds — the pattern of tiredness often points to the cause before any blood is taken.

2. Referral issued

You attend a Randox Health clinic for the sample.

3. Results reviewed with you

Not a set of numbers by email. A GP goes through what was found, what it explains, and what to do about it.

Preparation required

A morning sample after an overnight fast is preferred, for accurate glucose and iron results. Water is fine.

Stop iron supplements 48 hours beforehand. If you take B12 supplements or have had recent injections, tell the GP — both make the result harder to interpret. Biotin supplements distort thyroid results and should be stopped 48 hours before.

Understanding your results

The order in which things get found

In practice the commonest findings are, roughly in order: iron deficiency, vitamin D deficiency, thyroid disease, B12 or folate deficiency, prediabetes, and coeliac disease.

Together those account for a large proportion of the people who come in exhausted with no obvious explanation — and every one of them is treatable.

Ferritin is where most of the answers are

You can be significantly iron deficient with a completely normal full blood count and no anaemia. Ferritin is what shows it, and it is the test most often left out.

A ferritin in the low end of "normal" frequently causes real fatigue, particularly in menstruating women — and treating it makes a genuine difference. A haemoglobin that is fine is not the same as iron stores that are fine.

What a completely normal set of results means

It does not mean nothing is wrong. That deserves saying directly, because it is where a great many people get stuck.

The commonest causes of persistent fatigue do not show up in blood at all:

  • Sleep apnoea — substantially underdiagnosed, particularly in women, where it presents as fatigue and insomnia rather than snoring
  • Depression and anxiety, which cause profound physical tiredness
  • Chronic insufficient sleep, which is extremely common and rarely volunteered
  • Long COVID and post-viral fatigue
  • ME/CFS, which has no diagnostic blood test and is diagnosed clinically
  • Medication side effects — beta blockers, antihistamines, some antidepressants

Normal bloods narrow the field. They do not close the case.

The red flags that change the approach

Unintentional weight loss, drenching night sweats, new lumps, or fatigue that is worsening rapidly need urgent assessment rather than a routine screen — and should go through your NHS GP, who can refer on an urgent pathway.

What this test cannot tell you

What this panel cannot tell you

  • Whether you have sleep apnoea, which is one of the commonest causes and needs a sleep study
  • Whether depression is contributing, which no blood test measures and which is extremely common alongside fatigue
  • Whether you have ME/CFS or long COVID. Both are clinical diagnoses with no confirming test
  • Whether you are simply not sleeping enough, which is the answer more often than anyone likes

The most useful thing this test does

It excludes the treatable medical causes. That is genuinely valuable — but excluding them is not the same as explaining the fatigue.

A normal result should move the conversation on to sleep, mood and life circumstances, not end it.

The tests that will not help

"Adrenal fatigue" testing has no basis — the condition is not recognised, and salivary cortisol panels sold to diagnose it are not valid. Genuine adrenal insufficiency is a real and serious diagnosis, made differently, and it is rare.

Also without value here: food intolerance panels, hair mineral analysis, and "chronic fatigue" supplement protocols.

What we cannot do

Examine you — which matters for lymph nodes, thyroid and abdominal findings. Where anything in the history suggests it, you need seeing in person.

Costs explained

What you pay

  • £40 for the consultation
  • The panel, quoted before it is arranged
  • £40 for the results review

The free route

This is exactly what an NHS GP investigates, free — and "tired all the time" is one of the commonest reasons people see one. The standard NHS panel covers most of what is here.

If you can get an appointment, start there. What we offer is speed and the time to go through it properly, not a better blood test.

Free vitamin D supplements are available for some groups, and NHS Talking Therapies takes self-referrals without a GP — worth knowing, because depression is a commoner cause of fatigue than most people expect.

Where the fee earns its place

Twenty minutes. Fatigue is the symptom most poorly served by a ten-minute appointment, because the useful part is the history — sleep, mood, alcohol, medication, weight, periods, and what changed and when.

That conversation finds more answers than the panel does.

Where not to spend money

  • "Adrenal fatigue" or salivary cortisol testing — not a recognised condition, not a valid test
  • Food intolerance panels and hair mineral analysis
  • Energy and "mitochondrial support" supplements, which do not address any of the real causes
  • High-dose B12 supplements before testing, which make the result uninterpretable

Common questions

How should I prepare?

A morning fasted sample is preferred.

Stop iron supplements 48 hours beforehand, as they falsely raise the reading, and stop biotin 48 hours beforehand — it interferes with thyroid assays and can produce results that look like thyroid disease when there is none.

Tell us if you take B12 supplements, because they make that result uninterpretable.

My bloods came back normal. So why am I exhausted?

Because the commonest causes of fatigue do not appear in blood.

Sleep apnoea, depression, chronic insufficient sleep, post-viral fatigue and ME/CFS all run with entirely normal results — and every one is real.

Normal bloods narrow the field. They do not mean nothing is wrong, and they are not where the conversation should stop.

What gets found most often?

Iron deficiency, by some margin — then vitamin D deficiency, thyroid disease, B12 or folate deficiency, prediabetes and coeliac disease.

All treatable, which is the point of looking.

My haemoglobin was normal. Can I still be iron deficient?

Yes — and this is the single most useful thing on this page.

Iron deficiency without anaemia is common and causes genuine fatigue, particularly in menstruating women. Ferritin shows it; a full blood count does not.

A ferritin at the low end of the reference range is frequently worth treating.

Could it be my thyroid?

Possibly, and it is checked. Thyroid antibodies matter too — they can indicate autoimmune thyroid disease before TSH becomes abnormal.

And stop biotin 48 hours before, or the thyroid results may be wrong in a way that looks convincing.

What about adrenal fatigue?

It is not a recognised diagnosis, and the tests sold to diagnose it are not valid.

Genuine adrenal insufficiency — Addison's disease — is real, serious and rare, and diagnosed quite differently. We would test for it where the picture actually fits.

Could it be sleep apnoea?

Very possibly, and it is substantially underdiagnosed — particularly in women, where it presents as fatigue, insomnia and low mood rather than loud snoring.

Worth asking about if you wake unrefreshed however long you sleep, or if a partner has noticed pauses in your breathing. It needs a sleep study, and NHS referral is free.

Could it be depression?

Yes, and it is one of the commonest causes. Depression causes profound physical exhaustion, not only low mood.

NHS Talking Therapies accepts self-referrals without going through a GP, and it is free.

When should I be worried?

Unintentional weight loss, drenching night sweats, new lumps, or fatigue getting rapidly worse.

Those need urgent assessment through your NHS GP, who can refer on an urgent pathway. Do not route that through a private blood test.

Dr Mohammad Zubair Khan, GMC-registered private GP and founder of Cheshire Clinics

Clinically reviewed by Dr Mohammad Zubair Khan, GMC 7563469

Last reviewed

August 23, 2026

How it works

What happens when you book

£40 for a 20-minute appointment with a GMC-registered GP, 6am to 10pm, seven days a week. Membership is optional and never required.
Cheshire Clinics online GP appointment booking confirmation on mobile
01

Book your appointment

Pick a time that suits you — 6am to 10pm, seven days a week, including weekends and bank holidays. £40 for 20 minutes, self-pay, with no insurance to arrange.
5–10 minutes
Online video consultation with a GMC-registered private GP
02

Meet your GP

A 20-minute video or phone consultation with a GMC-registered GP — long enough for a proper conversation about your symptoms, your history and what matters to you.
20 minutes
Diagnostic testing plan including blood test panel, ECG and urine screening
03

Tests and referrals, if you need them

Where testing will actually answer the question, we arrange it — blood tests and health screening through our laboratory partner, or a referral for ultrasound, X-ray, CT or MRI through private imaging providers. We will also tell you when a scan is not the right next step.
1–7 days
Personalised results and treatment plan from a private GP consultation
04

Results and next steps

Your GP talks you through what the results mean and agrees the next step with you. Every consultation ends with your treatment plan in writing, and any prescription goes to your own pharmacy.
20 minutes
GP follow-up reminder for ongoing care and progress monitoring
05

Ongoing care and follow-up

Follow-up appointments, progress monitoring and ongoing advice — including saying plainly when something needs in-person or NHS care instead.

Ongoing

How we compare

Time to be seen

Appointment length

Your NHS record in the room

Written treatment plan

Told when a test isn’t needed

Cost

Varies by practice

Typically 10 minutes

Yes, your full record

Not routinely

Usually

Free

Same day

Often 10 to 15 minutes

Usually not

Sometimes charged

Varies by provider

Often a subscription

Questions about our service

How quickly can I be seen?

Same-day access is usually available, from 6am to 10pm, seven days a week. You choose a time that suits you rather than waiting on hold at 8am.

Will I see the same doctor each time?

Yes. Care is led personally by Dr Mohammad Khan, so you are not passed between clinicians. Continuity is the point of a small practice: someone who knows your history and is listening attentively rather than working through a checklist.

Can you see my NHS records?

Yes, with your consent. We can access your Summary Care Record during the consultation, so your current medications, allergies and significant history are in the room. That means fewer questions you have already answered elsewhere, and safer prescribing.

Are you trying to replace my NHS GP?

No. We are not here to replace GPs, only to support them. Your NHS practice remains responsible for your ongoing care, and with your consent we write to them after the consultation. We are useful when you need to be seen sooner, or want more time than a standard appointment allows.

What is included in the appointment?

Twenty unhurried minutes and a comprehensive assessment. A written treatment plan is included, along with any prescription, sick note or referral letter arising from the consultation, at no extra charge.

How much does it cost?

£40 for 20 minutes, self-pay. Membership is optional and never required. Priced for fairness, because we are not here to charge extortionate amounts for access to a doctor.

What does “treatable online” actually mean?

It means the diagnosis can usually be made from your history and photographs, and that treatment can be arranged safely without examining you. Where a condition is not marked treatable online, it is because examination is the diagnosis — listening to a chest, feeling an abdomen, examining an ear or a joint — or because a procedure or device is needed.

Can you prescribe antibiotics?

Yes, where there is a genuine bacterial infection — cellulitis, impetigo, bacterial urine infections, confirmed strep throat. We will also frequently tell you that you do not need one. Most sore throats, coughs, colds and earaches are viral, and an antibiotic gives you the side effects with none of the benefit.

What if the GP cannot help with what I need?

If your problem turns out to be genuinely outside what we can do remotely, the doctor will tell you straight away, point you to the right service, and refund your fee in full. We would rather do that than fill twenty minutes to justify the charge.

What should I do in an emergency?

Call 999 or go to A&E — do not book an online appointment and do not wait for a reply to an email. For urgent problems that are not emergencies, NHS 111 is available 24 hours a day, online or by phone, and can direct you to the right service.

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