An artery is a vessel that carries blood away from the heart. Arteries have thick, muscular, elastic walls able to withstand the pressure generated by each heartbeat.
Almost all arteries carry oxygenated blood; the pulmonary arteries are the exception, carrying deoxygenated blood from the heart to the lungs. The smallest arteries are called arterioles.
Arterial disease characteristically causes problems of supply — pain on exertion, tissue damage, or sudden loss of function when a vessel blocks.
Named individually in reports: the coronary arteries supplying the heart, the carotid arteries supplying the brain, the femoral arteries supplying the legs.
Atherosclerosis describes the build-up of fatty plaque within arterial walls and underlies most arterial disease.
Arterial narrowing is the mechanism behind angina, most strokes and peripheral arterial disease. The risk factors are shared: smoking, high blood pressure, raised cholesterol, diabetes and inactivity.
Sudden complete arterial blockage is a time-critical emergency, whether in the heart, brain or a limb.

Clinically reviewed by Dr Mohammad Zubair Khan, GMC 7563469
Last reviewed
August 30, 2026