Words in your letters

P

Prophylaxis

Treatment given to prevent something rather than to treat it.

Also called:

Preventive treatment, prophylactic, pre-exposure prophylaxis, PrEP

Pronounced:

proff-i-LAK-sis

What it means

Anything given to prevent a problem rather than to treat one that has already happened.

Common examples: malaria tablets before travel, antibiotics before an operation, blood thinners after surgery, PrEP to prevent HIV, and daily medication to prevent migraines.

The key implication is that you take it while feeling completely well, which is precisely why adherence is the main problem with all of it.

In practice

On prescriptions, travel clinic advice, and surgical discharge letters.

"Prophylactic" is the adjective, as in a prophylactic antibiotic.

Why it matters

Ask how long to continue. This is where prophylaxis most often goes wrong — malaria tablets, for instance, must continue for weeks after you return, and stopping at the airport is a recognised failure.

Ask what it does and does not protect against. No prophylaxis is complete, and knowing the residual risk matters.

Set a reminder. Taking something daily while feeling fine is genuinely hard, and it is the whole basis of whether it works.

Dr Mohammad Zubair Khan, GMC-registered private GP and founder of Cheshire Clinics

Clinically reviewed by Dr Mohammad Zubair Khan, GMC 7563469

Last reviewed

August 30, 2026

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